Klacid/Klacid MR Description

Clarithromycin is a semi-synthetic macrolide antibiotic obtained by substitution of CH₃O group for the hydroxyl (OH) group at position 6 of the erythromycin lactonic ring. Specifically clarithromycin is 6-O-methyl erythromycin. The white to off-white antibiotic powder is bitter, practically odorless, essentially insoluble in water, and slightly soluble in ethanol, methanol, and acetonitrile. Its molecular weight is 747.96.
Klacid tab: One tablet contains clarithromycin 250 mg.
Klacid MR: One tablet contains clarithromycin 500 mg.
Klacid Ped oral susp: After mixing, each 5 mL of the granules for suspension contains 125 mg of clarithromycin.
Excipient: Sucrose 536 mg/ml.
Clarithromycin pediatric suspension is an oral dosage form of clarithromycin for use primarily in children.
Excipients/Inactive Ingredients: Klacid tab: Sodium Content: 6.1 mg. Tablet Core: Sodium croscarmellose, microcrystalline cellulose, silicon dioxide, povidone, stearic acid, magnesium stearate and talc. Tablet Coating, Colour and Glass Coating: Hypromellose, sorbitan monooleate, propylene glycol, titanium dioxide, vanillin, quinoline yellow (E104 aluminium lake) and sorbic acid.
Klacid Ped oral susp: Clarithromycin pediatric suspension consists of a granulation of clarithromycin and carbopol which is coated with HP-55 polymer (hydroxypropyl methylcellulose phthalate). The coated granules are mixed with a blend of inactive ingredients, such as sucrose, xanthan gum, silicon dioxide, potassium sorbate, citric acid, maltodextrin, titanium dioxide, flavoring, etc. Water is added to reconstitute the suspension prior to use.
Klacid MR: Sodium Content: 15.3 mg/tablet. Tablet Core: Citric acid, sodium alginate, sodium calcium alginate, lactose (115 mg), povidone, talc, stearic acid and magnesium stearate. Coating Solution: Hypromellose, polyethylene glycol, titanium dioxide, quinoline yellow (E104 aluminium lake) and sorbic acid.